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Predictors of outcome of anorectal biofeedback therapy in patients with constipation.
Aliment Pharmacol Ther 2011; 33: 1245-1251 SUMMARY: Background Anorectal biofeedback therapy (BFT) is a safe and effective treatment in patients with constipation. Given the high prevalence of constipation and therefore high demand for BFT, there is a need to prioritise patients. Aims To explore clinical features and anorectal physiology which predict success or failure of BFT and to derive a statistical model which helps to predict the success of BFT. Methods A total of 102 patients with constipation referred for BFT were evaluated. All patients underwent comprehensive clinical and anorectal function assessment, including balloon expulsion testing. The BFT protocol consisted of a comprehensive 6-weekly visit programme comprising instruction on toilet behaviour and abdominal breathing, achieving adequate rectal pressure and anal relaxation, and balloon expulsion and rectal sensory retraining. Success of BFT was based on an improvement in global bowel satisfaction. Results Harder stool consistency (P = 0.009), greater willingness to participate (P < 0.001), higher resting anal sphincter pressure (P = 0.04) and prolonged balloon expulsion time (P = 0.02) correlated with an improvement in bowel satisfaction score. A longer duration of laxative use (P = 0.049) correlated with no improvement in bowel satisfaction score. Harder stools, shorter duration of laxative use, higher straining rectal pressure and prolonged balloon expulsion independently predicted successful BFT. A model (, where ß represents a regression coefficient, X is a given predictive variable and S(i) is the weighted index score for each individual) incorporating these four variables enabled prediction of successful BFT, with sensitivity and specificity of 0.79 and 0.81, respectively. Conclusions Important clinical and anorectal physiological features were found to be associated with outcome of anorectal biofeedback therapy in patients with constipation. This information and the predictive model will assist clinicians to prioritise patients for anorectal biofeedback therapy.
Aliment Pharmacol Ther. 2011 Jun;33(11):1245-51. doi: 10.1111/j.1365-2036.2011.04653.x. Epub 2011 Apr 6. Shim LS, Jones M, Prott GM, Morris LI, Kellow JE, Malcolm A. Gastrointestinal Investigation Unit, Royal North Shore Hospital and University of Sydney, Sydney, NSW, Australia. Department of Psychology, Macquarie University, North Ryde, NSW, Australia.
Excessive worry and anxieties are so common in Western society that I sincerely doubt that there are many people who are not adversely affected by them. Do you constantly feel stressed? Do you have problems sleeping? Is your mind always hyperactive and jumping from worry to worry? Yes, you problem are handling your stress and anxieties very well.
Remember that your reactions are most likely part of what psychologists call learned behavior. This means that at some time you reacted – or over-reacted – to a situation. When you perceived it happening again, this recognition...
For many people, cigarette smoking began at an early age. Usually this habit starts during a person’s teen years although we have seen it start even earlier. Normally, peer pressure or the influence or the example of parents was somehow involved in the decision to smoke the first cigarette. Also, depending on a person’s age, they may have been influenced by advertising, which was legal at one time in America.
Once this “social reason” for smoking initiated the act, there are two basic reasons why the act of smoking became and addiction. First is the addictive nature of nicotine. Nicotine...
If you are anything like me, by the time you reached maturity there were probably numerous things in your history that you regret. These could be things that you said or did – or even failed to do. Indeed, we go through life with this ever growing collection of stuff that we wish we could discard. How we look at those events or failings determines much about your current and future behavior. Your relationships with others and your health can easily become victim to your inability to release the bonds that guilt place on our mind, body, and soul.